NeoMTA 2 Clinical Research
Delikan, Ebru & Aksu, Seçkin. (2020). Comparison of the sealing ability of apical plug materials in simulated open apices: An in vitro study. Journal of Oral Research and Review. 12. 70. 10.4103/jorr.jorr_41_19.
COMPARISON OF THE SEALING ABILITY OF APICAL PLUG MATERIALS IN SIMULATED OPEN APICES: AN IN VITRO STUDY
PURPOSE
The aim of this study was to evaluate the microleakage of apical plugs made of four different materials in simulated immature teeth.
METHODS
Ninety extracted single-rooted teeth were selected and randomly divided into six groups according to the materials used: NeoMTA, EndoSequence Bioceramic Root Repair Material Fast Set Putty (BC RRM-FS), Biodentine, Endo Repair, negative control, and positive control group. Microleakage was evaluated by using a stereomicroscope to assess the penetration of methylene blue solution. Data were analyzed using descriptive statistics and Pearson's Chi-square test (P <0.05).
RESULTS
EndoRepair group showed the highest leakage, and NeoMTA group exhibited the best sealing ability of apical plugs. The sealing ability of Biodentine was similar to NeoMTA and BC RRM-FS. On the other hand, the sealing ability of BC RRM-FS significantly lower than NeoMTA, but it provided a better sealing than EndoRepair.
CONCLUSION
According to the results of this study, NeoMTA and Biodentine can be used safely as apical plug material in single-session apexification in immature teeth. The BC RRM-FS, on the other hand, provided an acceptable sealing, although not as successful as the NeoMTA. However, the sealing properties of Endo Repair need to be improved.
COMPARISON OF THE SEALING ABILITY OF APICAL PLUG MATERIALS IN SIMULATED OPEN APICES: AN IN VITRO STUDY
PURPOSE
The aim of this study was to evaluate the microleakage of apical plugs made of four different materials in simulated immature teeth.
METHODS
Ninety extracted single-rooted teeth were selected and randomly divided into six groups according to the materials used: NeoMTA, EndoSequence Bioceramic Root Repair Material Fast Set Putty (BC RRM-FS), Biodentine, Endo Repair, negative control, and positive control group. Microleakage was evaluated by using a stereomicroscope to assess the penetration of methylene blue solution. Data were analyzed using descriptive statistics and Pearson's Chi-square test (P <0.05).
RESULTS
EndoRepair group showed the highest leakage, and NeoMTA group exhibited the best sealing ability of apical plugs. The sealing ability of Biodentine was similar to NeoMTA and BC RRM-FS. On the other hand, the sealing ability of BC RRM-FS significantly lower than NeoMTA, but it provided a better sealing than EndoRepair.
CONCLUSION
According to the results of this study, NeoMTA and Biodentine can be used safely as apical plug material in single-session apexification in immature teeth. The BC RRM-FS, on the other hand, provided an acceptable sealing, although not as successful as the NeoMTA. However, the sealing properties of Endo Repair need to be improved.
Nagas, Emre & Ertan, Ahmet & Eymirli, Ayhan & Uyanik, Mehmet & Cehreli, Zafer. (2021). Tooth Discoloration Induced by Different Calcium Silicate-Based Cements: A Two-Year Spectrophotometric and Photographic Evaluation in Vitro. The Journal of clinical pediatric dentistry. 45. 112-116. 10.17796/1053-4625-45.2.7.
TOOTH DISCOLORATION INDUCED BY DIFFERENT CALCIUM SILICATE-BASED CEMENTS: A TWO-YEAR SPECTROPHOTOMETRIC AND PHOTOGRAPHIC EVALUATION IN VITRO
PURPOSE
Calcium silicate-based cements (CSCs) may lead to coronal staining in young permanent teeth over the time. The purpose of this study was to evaluate and compare the long-term tooth discoloration induced by different CSCs.
METHODS
Ninety freshly-extracted human molars were assigned randomly into 6 groups (n=15/group) according to the CSC used as a pulpotomy material: ProRoot MTA, MTA Angelus, NeoMTA, EndoSequence Putty, Biodentine and Negative control (No cement). The color was assessed at baseline, and thereafter at 3, 6, 12 and 24 months by using both a spectrophotometer and digital images taken with and without a cross-polarizing filter. The time-dependent changes in color (ΔE) were compared within and among groups using Analysis of Variance.
RESULTS
Angelus MTA and ProRooT MTA showed severe coronal discoloration (p>0.05) starting at 3 months. ΔE values of NeoMTA, EndoSequence Bioceramic Putty and Biodentine were below the perceptibility threshold, with Biodentine showing greater ΔE values than NeoMTA and EndoSequence Putty in the absence of statistical significance (p>0.05).
CONCLUSION
Discoloration elicited by CSCs may develop soon after placement, and continue to increase for up to two years. Angelus MTA and ProRooT MTA cannot be recommended for vital pulp therapies in the esthetic zone of young individuals.
TOOTH DISCOLORATION INDUCED BY DIFFERENT CALCIUM SILICATE-BASED CEMENTS: A TWO-YEAR SPECTROPHOTOMETRIC AND PHOTOGRAPHIC EVALUATION IN VITRO
PURPOSE
Calcium silicate-based cements (CSCs) may lead to coronal staining in young permanent teeth over the time. The purpose of this study was to evaluate and compare the long-term tooth discoloration induced by different CSCs.
METHODS
Ninety freshly-extracted human molars were assigned randomly into 6 groups (n=15/group) according to the CSC used as a pulpotomy material: ProRoot MTA, MTA Angelus, NeoMTA, EndoSequence Putty, Biodentine and Negative control (No cement). The color was assessed at baseline, and thereafter at 3, 6, 12 and 24 months by using both a spectrophotometer and digital images taken with and without a cross-polarizing filter. The time-dependent changes in color (ΔE) were compared within and among groups using Analysis of Variance.
RESULTS
Angelus MTA and ProRooT MTA showed severe coronal discoloration (p>0.05) starting at 3 months. ΔE values of NeoMTA, EndoSequence Bioceramic Putty and Biodentine were below the perceptibility threshold, with Biodentine showing greater ΔE values than NeoMTA and EndoSequence Putty in the absence of statistical significance (p>0.05).
CONCLUSION
Discoloration elicited by CSCs may develop soon after placement, and continue to increase for up to two years. Angelus MTA and ProRooT MTA cannot be recommended for vital pulp therapies in the esthetic zone of young individuals.
Cordell, Samantha & Kratunova, Evelina & Marion, Ian & Alrayyes, Sahar & Alapati, Satish. (2021). A Randomized Controlled Trial Comparing the Success of Mineral Trioxide Aggregate and Ferric Sulfate as Pulpotomy Medicaments for Primary Molars. Journal of dentistry for children (Chicago, Ill.). 88. 120-128..
A Randomized Controlled Trial Comparing the Success of Mineral Trioxide Aggregate and Ferric Sulfate as Pulpotomy Medicaments for Primary Molars
PURPOSE
To evaluate and compare the clinical and radiographic performance of a new type of mineral trioxide aggregate (MTA, NuSmile® NeoMTA®) and ferric sulfate (FS) as pulpotomy medicaments for primary molars over 12 months.
METHODS
Fifty participants (25 per group) were enrolled, according to specific inclusion criteria. Each participant received a single primary molar pulpotomy either with MTA or FS, depending on random digit table method allocation. Fifteen pediatric dental residents completed all pulpotomies, supervised by specialist faculty. Two calibrated examiners performed outcome assessments according to standardized criteria. Every six months, the study teeth were evaluated clinically and every 12 months radiographically. The inter- and intraexaminer reliability was assessed using Cohen's kappa, and the chi-square test was used for statistical analysis.
RESULTS
At six months, 42 participants (21 in each group) returned for evaluation. The FS group showed 95.2 percent clinical success compared to 100 percent for the MTA group. At the 12-month clinical and radiographic evaluation, the return sample consisted of 29 participants (14 in the MTA group, 15 in the FS group). FS had 86.6 percent clinical success and 60 percent radiographic success, while MTA showed 100 percent clinical and radiographic success. At 12 months, MTA showed a statistically significantly higher success rate compared to FS (P = 0.008). Examiner reliability was excellent with a kappa score greater than 0.88.
CONCLUSION
At 12 months, MTA showed superior success as a pulpotomy medicament in primary molars compared to FS.
A Randomized Controlled Trial Comparing the Success of Mineral Trioxide Aggregate and Ferric Sulfate as Pulpotomy Medicaments for Primary Molars
PURPOSE
To evaluate and compare the clinical and radiographic performance of a new type of mineral trioxide aggregate (MTA, NuSmile® NeoMTA®) and ferric sulfate (FS) as pulpotomy medicaments for primary molars over 12 months.
METHODS
Fifty participants (25 per group) were enrolled, according to specific inclusion criteria. Each participant received a single primary molar pulpotomy either with MTA or FS, depending on random digit table method allocation. Fifteen pediatric dental residents completed all pulpotomies, supervised by specialist faculty. Two calibrated examiners performed outcome assessments according to standardized criteria. Every six months, the study teeth were evaluated clinically and every 12 months radiographically. The inter- and intraexaminer reliability was assessed using Cohen's kappa, and the chi-square test was used for statistical analysis.
RESULTS
At six months, 42 participants (21 in each group) returned for evaluation. The FS group showed 95.2 percent clinical success compared to 100 percent for the MTA group. At the 12-month clinical and radiographic evaluation, the return sample consisted of 29 participants (14 in the MTA group, 15 in the FS group). FS had 86.6 percent clinical success and 60 percent radiographic success, while MTA showed 100 percent clinical and radiographic success. At 12 months, MTA showed a statistically significantly higher success rate compared to FS (P = 0.008). Examiner reliability was excellent with a kappa score greater than 0.88.
CONCLUSION
At 12 months, MTA showed superior success as a pulpotomy medicament in primary molars compared to FS.
Alsanouni, Munerah & Bawazir, Omar. (2019). A Randomized Clinical Trial of NeoMTA Plus in Primary Molar Pulpotomies. Pediatric dentistry. 15;41. 107-111.
A Randomized Clinical Trial of NeoMTA Plus in Primary Molar Pulpotomies
PURPOSE
The purpose of this study was to compare the success of pulpotomies in primary molars using a new type of mineral trioxide aggregate (MTA; NeoMTA Plus) with a conventional MTA (ProRoot MTA) as a pulpotomy medicament in primary molars.
METHODS
Eighty primary teeth in 28 patients were divided randomly, with 40 teeth in a control group (ProRoot MTA) and 40 teeth in an experimental group (NeoMTA Plus). A standardized pulpotomy technique was performed for each tooth. Clinical and radiographic follow-up examinations were conducted at three, six, and 12 months.
RESULTS
At 12 months, the clinical success for ProRoot MTA was 97.4 percent (38 out of 39) and the radiographic success was 94.9 percent (37 out of 39); for NeoMTA Plus, the clinical success was 100 percent (40 out of 40) and the radiographic success was 97.5 percent (39 out of 40). No significant differences were found between the two groups at all follow-up evaluations.
CONCLUSION
NeoMTA Plus showed a high percent success, similar to that of ProRoot MTA. NeoMTA Plus is a potential pulpotomy medicament for primary teeth.
A Randomized Clinical Trial of NeoMTA Plus in Primary Molar Pulpotomies
PURPOSE
The purpose of this study was to compare the success of pulpotomies in primary molars using a new type of mineral trioxide aggregate (MTA; NeoMTA Plus) with a conventional MTA (ProRoot MTA) as a pulpotomy medicament in primary molars.
METHODS
Eighty primary teeth in 28 patients were divided randomly, with 40 teeth in a control group (ProRoot MTA) and 40 teeth in an experimental group (NeoMTA Plus). A standardized pulpotomy technique was performed for each tooth. Clinical and radiographic follow-up examinations were conducted at three, six, and 12 months.
RESULTS
At 12 months, the clinical success for ProRoot MTA was 97.4 percent (38 out of 39) and the radiographic success was 94.9 percent (37 out of 39); for NeoMTA Plus, the clinical success was 100 percent (40 out of 40) and the radiographic success was 97.5 percent (39 out of 40). No significant differences were found between the two groups at all follow-up evaluations.
CONCLUSION
NeoMTA Plus showed a high percent success, similar to that of ProRoot MTA. NeoMTA Plus is a potential pulpotomy medicament for primary teeth.